Chemicals and Drugs

Vitamin B 6

VITAMIN B 6 refers to several PICOLINES (especially PYRIDOXINE; PYRIDOXAL; & PYRIDOXAMINE) that are efficiently converted by the body to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, and aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into PYRIDOXAMINE phosphate. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990). Most of vitamin B6 is eventually degraded to PYRIDOXIC ACID and excreted in the urine.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

VITAMIN B 6 refers to several PICOLINES (especially PYRIDOXINE; PYRIDOXAL; & PYRIDOXAMINE) that are efficiently converted by the body to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, and aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into PYRIDOXAMINE phosphate. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990). Most of vitamin B6 is eventually degraded to PYRIDOXIC ACID and excreted in the urine.

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

1 entry terms
  • Vitamin B6

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

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Indexing Annotation

/ther use: coordinate with disease /drug ther, not /diet ther

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History Note

2002; use PYRIDOXINE 1963-2001

MeSH Record

Previous Indexing

  • Pyridoxine (1965-2001)

MeSH Hierarchy

Tree Number

  1. D03w.383.725w.676w.925w

MeSH Record

NLM Classification

QU 187

AMA Style

References

  1. National Library of Medicine. Vitamin B 6. Medical Subject Headings (MeSH). 2026. Unique ID D025101. http://id.nlm.nih.gov/mesh/2026/D025101
  2. Vitamin B 6. In: Wikipedia. https://en.wikipedia.org/wiki/Vitamin_B6
  3. Vitamin B 6. In: Wikidata. https://www.wikidata.org/wiki/Q205130