Chemicals and Drugs

Voltage-Dependent Anion Channels

A family of voltage-gated eukaryotic porins that form aqueous channels. They play an essential role in mitochondrial CELL MEMBRANE PERMEABILITY, are often regulated by BCL-2 PROTO-ONCOGENE PROTEINS, and have been implicated in APOPTOSIS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of voltage-gated eukaryotic porins that form aqueous channels. They play an essential role in mitochondrial CELL MEMBRANE PERMEABILITY, are often regulated by BCL-2 PROTO-ONCOGENE PROTEINS, and have been implicated in APOPTOSIS.

MeSH Record

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MeSH Record

Synonyms

12 entry terms
  • Pore Forming Protein VDAC
  • VDAC Proteins
  • Voltage-Dependent Anion Channel
  • Voltage-Dependent, Anion-Selective Channels
  • Anion Channel, Voltage-Dependent
  • Anion Channels, Voltage-Dependent
  • Anion-Selective Channels Voltage-Dependent
  • Channel, Voltage-Dependent Anion
  • Channels Voltage-Dependent, Anion-Selective
  • Voltage Dependent Anion Channel
  • Voltage Dependent Anion Channels
  • Voltage Dependent, Anion Selective Channels

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

general; prefer specifics

MeSH Record

History Note

2006(1985)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.530w.400w.500w.520w
  2. D12.776w.543w.550w.450w.730w.520w
  3. D12.776w.543w.585w.400w.730w.520w

AMA Style

References

  1. National Library of Medicine. Voltage-Dependent Anion Channels. Medical Subject Headings (MeSH). 2026. Unique ID D050994. http://id.nlm.nih.gov/mesh/2026/D050994
  2. Voltage-Dependent Anion Channels. In: Wikipedia. https://en.wikipedia.org/wiki/Voltage-dependent_anion_channel
  3. Voltage-Dependent Anion Channels. In: Wikidata. https://www.wikidata.org/wiki/Q7940725