Structured Summary
Abstract
A triazole antifungal agent that specifically inhibits STEROL 14-ALPHA-DEMETHYLASE and CYTOCHROME P-450 CYP3A.
Chemical Identity
Chemical Information
- Molecular Formula
- C16H14F3N5O
- Molecular Weight
- 349.31 g/mol
- CAS Registry No.
- 137234-62-9
- IUPAC Name
- (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol
- InChIKey
- BCEHBSKCWLPMDN-MGPLVRAMSA-N
- SMILES
- C[C@@H](C1=NC=NC=C1F)[C@](CN2C=NC=N2)(C3=C(C=C(C=C3)F)F)O
- MeSH Unique ID
- D065819
- Source
- PubChem CID 71616
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Loading graph…
Drag nodes to rearrange; hover to trace links; click a node to open its page.
Drug Class
Pharmacological Action
MeSH Record
Synonyms
7 entry terms
- UK 109,496
- UK 109496
- UK-109,496
- UK-109496
- Vfend
- UK109,496
- UK109496
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2015
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Voriconazole. Medical Subject Headings (MeSH). 2026. Unique ID D065819. http://id.nlm.nih.gov/mesh/2026/D065819
- Voriconazole. In: Wikipedia. https://en.wikipedia.org/wiki/Voriconazole
- Voriconazole. In: Wikidata. https://www.wikidata.org/wiki/Q412236
- Voriconazole. In: PubChem Compound. CID 71616. https://pubchem.ncbi.nlm.nih.gov/compound/71616