Chemicals and Drugs

Vortioxetine

A piperazine derivative that acts as a serotonin reuptake inhibitor, as a 5-HT3 receptor antagonist, and 5-HT1A receptor agonist. It is used for the treatment of anxiety and depression.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A piperazine derivative that acts as a serotonin reuptake inhibitor, as a 5-HT3 receptor antagonist, and 5-HT1A receptor agonist. It is used for the treatment of anxiety and depression.

Chemical Identity

Chemical Information

Molecular Formula
C18H22N2S
Molecular Weight
298.4 g/mol
CAS Registry No.
508233-74-7
IUPAC Name
1-[2-(2,4-dimethylphenyl)sulfanylphenyl]piperazine
InChIKey
YQNWZWMKLDQSAC-UHFFFAOYSA-N
SMILES
CC1=CC(=C(C=C1)SC2=CC=CC=C2N3CCNCC3)C
MeSH Unique ID
D000078784
Source
PubChem CID 9966051

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • 1-(2-(2,4-Dimethylphenylsulfanyl)phenyl)piperazine
  • Brintellix
  • Lu AA21004
  • Lu-AA21004
  • LuAA21004
  • Vortioxetine Hydrobromide

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (2011)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Vortioxetine. Medical Subject Headings (MeSH). 2026. Unique ID D000078784. http://id.nlm.nih.gov/mesh/2026/D000078784
  2. Vortioxetine. In: Wikipedia. https://en.wikipedia.org/wiki/Vortioxetine
  3. Vortioxetine. In: Wikidata. https://www.wikidata.org/wiki/Q3563148
  4. Vortioxetine. In: PubChem Compound. CID 9966051. https://pubchem.ncbi.nlm.nih.gov/compound/9966051