Structured Summary
Abstract
Isoforms encoded by the WT1 Wilms tumor suppressor gene (GENES, WILMS TUMOR) and produced by alternative splicings. They are zinc finger-containing transcription factors involved in both transactivation and repression, and are critical for normal development and function of the urogenital tract.
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Synonyms
5 entry terms
- WT1 Gene Product
- WT1 Protein
- Gene Product, WT1
- Protein, WT1
- Proteins, WT1
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
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History Note
2002; for WT1 PROTEIN use WT1 PROTEINS (NM) 1991-2001
MeSH Record
Previous Indexing
- DNA-Binding Proteins (1991-2001)
- Transcription Factors (1991-2001)
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AMA Style
References
- National Library of Medicine. WT1 Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D025721. http://id.nlm.nih.gov/mesh/2026/D025721
- WT1 Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q111292026