Chemicals and Drugs

X-Box Binding Protein 1

A basic leucine zipper transcription factor that regulates expression of MHC CLASS II GENES through its binding to a conserved X-box DNA sequence in the promoter region. It regulates the expression of genes involved in the UNFOLDED PROTEIN RESPONSE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A basic leucine zipper transcription factor that regulates expression of MHC CLASS II GENES through its binding to a conserved X-box DNA sequence in the promoter region. It regulates the expression of genes involved in the UNFOLDED PROTEIN RESPONSE.

MeSH Record

Classification

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MeSH Record

Synonyms

9 entry terms
  • TREB-5 Protein
  • TREB5 Protein
  • Tax-Responsive Element-Binding Protein 5
  • XBP-1 Protein
  • XBP2 Protein
  • TREB 5 Protein
  • Tax Responsive Element Binding Protein 5
  • X Box Binding Protein 1
  • XBP 1 Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017; use REGULATORY FACTOR X TRANSCRIPTION FACTORS (NM) 1988-2016

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. X-Box Binding Protein 1. Medical Subject Headings (MeSH). 2026. Unique ID D000071717. http://id.nlm.nih.gov/mesh/2026/D000071717
  2. X-Box Binding Protein 1. In: Wikidata. https://www.wikidata.org/wiki/Q21116794