Chemicals and Drugs

Xanthine Oxidase

An iron-molybdenum flavoprotein containing FLAVIN-ADENINE DINUCLEOTIDE that oxidizes hypoxanthine, some other purines and pterins, and aldehydes. Deficiency of the enzyme, an autosomal recessive trait, causes xanthinuria.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An iron-molybdenum flavoprotein containing FLAVIN-ADENINE DINUCLEOTIDE that oxidizes hypoxanthine, some other purines and pterins, and aldehydes. Deficiency of the enzyme, an autosomal recessive trait, causes xanthinuria.

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Classification

Broader headings

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MeSH Record

Synonyms

11 entry terms
  • Hypoxanthine Dehydrogenase
  • Hypoxanthine Oxidase
  • Hypoxanthine-Xanthine Oxidase
  • Purine-Xanthine Oxidase
  • Dehydrogenase, Hypoxanthine
  • Hypoxanthine Xanthine Oxidase
  • Oxidase, Hypoxanthine
  • Oxidase, Hypoxanthine-Xanthine
  • Oxidase, Purine-Xanthine
  • Oxidase, Xanthine
  • Purine Xanthine Oxidase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

/defic: consider also XANTHINES /urine (IM) + PURINE-PYRIMIDINE METABOLISM, INBORN ERRORS (IM)

MeSH Record

History Note

65

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Xanthine Oxidase. Medical Subject Headings (MeSH). 2026. Unique ID D014969. http://id.nlm.nih.gov/mesh/2026/D014969
  2. Xanthine Oxidase. In: Wikipedia. https://en.wikipedia.org/wiki/Xanthine_oxidase
  3. Xanthine Oxidase. In: Wikidata. https://www.wikidata.org/wiki/Q412509