Chemicals and Drugs

Yohimbine

A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of ERECTILE DYSFUNCTION.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of ERECTILE DYSFUNCTION.

Chemical Identity

Chemical Information

Molecular Formula
C21H26N2O3
Molecular Weight
354.4 g/mol
CAS Registry No.
146-48-5
IUPAC Name
methyl (1S,15R,18S,19R,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
InChIKey
BLGXFZZNTVWLAY-SCYLSFHTSA-N
SMILES
COC(=O)[C@H]1[C@H](CC[C@@H]2[C@@H]1C[C@H]3C4=C(CCN3C2)C5=CC=CC=C5N4)O
MeSH Unique ID
D015016
Source
PubChem CID 8969

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

15 entry terms
  • Aphrodine Hydrochloride
  • Aphrodyne
  • Corynanthine
  • Corynanthine Tartrate
  • Pluriviron
  • Rauhimbine
  • Rauwolscine
  • Yocon
  • Yohimbin Spiegel
  • Yohimbine Houdé
  • Yohimbine Hydrochloride
  • Yohimex
  • Hydrochloride, Aphrodine
  • Hydrochloride, Yohimbine
  • Tartrate, Corynanthine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

YOHIMBINE DERIVATIVES was see under YOHIMBINE 1975-77, was see under YOHIMBANS 1969-74

MeSH Hierarchy

Tree Numbers

  1. D03w.132w.436w.681.933w
  2. D03w.633.100.473.402w.681.933w
  3. D03w.633.100.496.500.500w.681.933w

AMA Style

References

  1. National Library of Medicine. Yohimbine. Medical Subject Headings (MeSH). 2026. Unique ID D015016. http://id.nlm.nih.gov/mesh/2026/D015016
  2. Yohimbine. In: Wikipedia. https://en.wikipedia.org/wiki/Yohimbine
  3. Yohimbine. In: Wikidata. https://www.wikidata.org/wiki/Q412226
  4. Yohimbine. In: PubChem Compound. CID 8969. https://pubchem.ncbi.nlm.nih.gov/compound/8969