Structured Summary
Abstract
Genetically engineered nucleases that cleave DNA at a defined distance from specific DNA sequences recognized by ZINC FINGER DNA-BINDING DOMAINS. They are composed of a DNA cleaving domain adapted from DNA endonucleases fused to a zinc finger DNA-binding domain.
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Classification
Broader headings
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Synonyms
9 entry terms
- Zinc Finger Nuclease
- Zinc-Finger Nuclease
- Zinc-Finger Nucleases
- Finger Nuclease, Zinc
- Finger Nucleases, Zinc
- Nuclease, Zinc Finger
- Nuclease, Zinc-Finger
- Nucleases, Zinc Finger
- Nucleases, Zinc-Finger
MeSH Record
Aspects Covered
26 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2018
MeSH Record
Previous Indexing
- Endonucleases (2005-2017)
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AMA Style
References
- National Library of Medicine. Zinc Finger Nucleases. Medical Subject Headings (MeSH). 2026. Unique ID D000075804. http://id.nlm.nih.gov/mesh/2026/D000075804
- Zinc Finger Nucleases. In: Wikipedia. https://en.wikipedia.org/wiki/Zinc-finger_nuclease
- Zinc Finger Nucleases. In: Wikidata. https://www.wikidata.org/wiki/Q204773