Structured Summary
Abstract
A transcriptional activator and oncogene protein that contains two CYS2-HIS2 ZINC FINGERS. Two isoforms are expressed; both regulate the expression of specific genes during development of craniofacial features, digits, the CENTRAL NERVOUS SYSTEM; and the GASTROINTESTINAL TRACT. They also regulate SONIC HEDGEHOG PROTEIN signaling and cell proliferation.
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Classification
Broader headings
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MeSH Record
Synonyms
7 entry terms
- Gli Protein
- Gli1 Protein
- Glioma-Associated Oncogene Protein
- Oncogene GLI Protein
- GLI Protein, Oncogene
- Glioma Associated Oncogene Protein
- Oncogene Protein, Glioma-Associated
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017 (1993)
MeSH Hierarchy
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AMA Style
References
- National Library of Medicine. Zinc Finger Protein GLI1. Medical Subject Headings (MeSH). 2026. Unique ID D000071676. http://id.nlm.nih.gov/mesh/2026/D000071676
- Zinc Finger Protein GLI1. In: Wikidata. https://www.wikidata.org/wiki/Q24775254