Chemicals and Drugs

Zinc Finger Protein Gli2

A transcriptional activator that contains five adjacent CYS2-HIS2 ZINC FINGERS. It functions in the hedgehog signaling pathway and is required for normal embryonic development. Mutations in the GLI2 gene are associated with type 9 HOLOPROSENCEPHALY and type 2 PALLISTER-HALL SYNDROME.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A transcriptional activator that contains five adjacent CYS2-HIS2 ZINC FINGERS. It functions in the hedgehog signaling pathway and is required for normal embryonic development. Mutations in the GLI2 gene are associated with type 9 HOLOPROSENCEPHALY and type 2 PALLISTER-HALL SYNDROME.

MeSH Record

Classification

Broader headings

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Synonyms

1 entry terms
  • Gli2 Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2018 (1997); use GLI2 PROTEIN 1997-2017

MeSH Hierarchy

Tree Numbers

  1. D12.776w.260w.755.925
  2. D12.776w.930w.900.850

AMA Style

References

  1. National Library of Medicine. Zinc Finger Protein Gli2. Medical Subject Headings (MeSH). 2026. Unique ID D000075746. http://id.nlm.nih.gov/mesh/2026/D000075746
  2. Zinc Finger Protein Gli2. In: Wikidata. https://www.wikidata.org/wiki/Q5513620