Structured Summary
Abstract
A zinc efflux transporter highly expressed by ISLET CELLS of the pancreas. It functions in the accumulation of zinc in intracellular vesicles and may be involved in INSULIN maturation and storage processes. Variations in the SLC30A8 gene are associated with susceptibility to DIABETES MELLITUS, TYPE 2.
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
Synonyms
4 entry terms
- Slc30A8 Protein
- Solute Carrier Family 30 Member 8 Protein
- ZnT-8 Protein
- ZnT 8 Protein
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2018
MeSH Record
Previous Indexing
- Cation Transport Proteins (2004-2017)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Zinc Transporter 8. Medical Subject Headings (MeSH). 2026. Unique ID D000075703. http://id.nlm.nih.gov/mesh/2026/D000075703
- Zinc Transporter 8. In: Wikidata. https://www.wikidata.org/wiki/Q24785798