Chemicals and Drugs

alpha-Crystallin B Chain

One of the alpha crystallin subunits. In addition to being expressed in the lens (LENS, CRYSTALLINE), alpha-crystallin B chain has been found in a variety of tissues such as HEART; BRAIN; MUSCLE; and KIDNEY. Accumulation of the protein in the brain is associated with NEURODEGENERATIVE DISEASES such as CREUTZFELDT-JAKOB SYNDROME and ALEXANDER DISEASE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

One of the alpha crystallin subunits. In addition to being expressed in the lens (LENS, CRYSTALLINE), alpha-crystallin B chain has been found in a variety of tissues such as HEART; BRAIN; MUSCLE; and KIDNEY. Accumulation of the protein in the brain is associated with NEURODEGENERATIVE DISEASES such as CREUTZFELDT-JAKOB SYNDROME and ALEXANDER DISEASE.

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Classification

Broader headings

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MeSH Record

Synonyms

9 entry terms
  • Crystallins, alpha B Chain
  • Rosenthal Fiber Component
  • alpha B-Crystallin
  • alpha-Crystallin, B Subunit
  • B Chain, alpha-Crystallin
  • B Subunit alpha-Crystallin
  • alpha B Crystallin
  • alpha Crystallin B Chain
  • alpha Crystallin, B Subunit

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2003; for ALPHA B-CRYSTALLIN use CRYSTALLINS 1998-2002

MeSH Record

Previous Indexing

  • Crystallins (1985-2002)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. alpha-Crystallin B Chain. Medical Subject Headings (MeSH). 2026. Unique ID D038203. http://id.nlm.nih.gov/mesh/2026/D038203
  2. alpha-Crystallin B Chain. In: Wikidata. https://www.wikidata.org/wiki/Q21100907