Chemicals and Drugs

alpha Subunit Glycoprotein Hormones

The alpha chain of pituitary glycoprotein hormones (THYROTROPIN; FOLLICLE STIMULATING HORMONE; LUTEINIZING HORMONE) and the placental CHORIONIC GONADOTROPIN. Within a species, the alpha subunits of these four hormones are identical; the distinct functional characteristics of these glycoprotein hormones are determined by the unique beta subunits. Both subunits, the non-covalently bound heterodimers, are required for full biologic activity.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The alpha chain of pituitary glycoprotein hormones (THYROTROPIN; FOLLICLE STIMULATING HORMONE; LUTEINIZING HORMONE) and the placental CHORIONIC GONADOTROPIN. Within a species, the alpha subunits of these four hormones are identical; the distinct functional characteristics of these glycoprotein hormones are determined by the unique beta subunits. Both subunits, the non-covalently bound heterodimers, are required for full biologic activity.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

23 entry terms
  • ASGPH
  • Chorionic Gonadotropin, alpha
  • Chorionic Gonadotropin, alpha Subunit
  • Common alpha Subunit Glycoprotein Hormones
  • FSH, alpha Subunit
  • FSH-alpha
  • Follicle Stimulating Hormone, alpha Subunit
  • Follicle-Stimulating Hormone, alpha Subunit
  • Glycoprotein Hormones, alpha Chain
  • Glycoprotein Hormones, alpha Polypeptide
  • Glycoprotein Hormones, alpha Subunit
  • LH, alpha Subunit
  • Luteinizing Hormone, alpha Subunit
  • Lutotropin-alpha
  • Pituitary Glycoprotein Hormone, alpha Subunit
  • TSH, alpha Subunit
  • TSH-alpha
  • Thyroid-Stimulating Hormone, alpha Subunit
  • Thyrotropin alpha Subunit
  • FSH alpha
  • Lutotropin alpha
  • TSH alpha
  • Thyroid Stimulating Hormone, alpha Subunit

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

coord with THYROTROPIN; FOLLICLE STIMULATING HORMONE; LUTEINIZING HORMONE; or CHORIONIC GONADOTROPIN if particularly discussed

MeSH Record

History Note

1989

MeSH Record

Previous Indexing

  • FSH (1972-1988)
  • Gonadotropins, Chorionic (1972-1988)
  • Gonadotropins, Pituitary (1972-1988)
  • LH (1972-1988)
  • Menotropins (1973-1988)
  • Pituitary Hormones, Anterior (1972-1988)
  • Thyrotropin (1972-1988)

MeSH Hierarchy

Tree Numbers

  1. D06.472w.699w.322w.326w.562
  2. D06.472w.699w.322w.576.288.750
  3. D06.472w.699w.322w.576.463w.249
  4. D06.472w.699w.631.525.343.288.750
  5. D06.472w.699w.631.525.343.463w.249
  6. D06.472w.699w.631.525.883w.249
  7. D06.472w.699w.649.367w.562
  8. D12.644w.548w.691.525.343.288.750
  9. D12.644w.548w.691.525.343.463w.249
  10. D12.644w.548w.691.525.883w.249
  11. D12.644w.548w.726.367w.562

AMA Style

References

  1. National Library of Medicine. alpha Subunit Glycoprotein Hormones. Medical Subject Headings (MeSH). 2026. Unique ID D015292. http://id.nlm.nih.gov/mesh/2026/D015292
  2. alpha Subunit Glycoprotein Hormones. In: Wikidata. https://www.wikidata.org/wiki/Q24739332