Chemicals and Drugs

beta-Arrestins

Non-visual system arrestins that negatively regulate G-PROTEIN-COUPLED RECEPTORS (GPCRs) and may also function independently of GPCR signaling. They bind and recruit many different signaling factors, including MITOGEN-ACTIVATED PROTEIN KINASES; SRC-FAMILY-KINASES; and FILAMIN to GPCRs and may recognize different phosphorylation states of the receptors to determine the specificity of the cellular response to signaling.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Non-visual system arrestins that negatively regulate G-PROTEIN-COUPLED RECEPTORS (GPCRs) and may also function independently of GPCR signaling. They bind and recruit many different signaling factors, including MITOGEN-ACTIVATED PROTEIN KINASES; SRC-FAMILY-KINASES; and FILAMIN to GPCRs and may recognize different phosphorylation states of the receptors to determine the specificity of the cellular response to signaling.

MeSH Record

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MeSH Record

Synonyms

3 entry terms
  • beta-Arrestin
  • beta Arrestin
  • beta Arrestins

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017 (1992)

MeSH Hierarchy

Tree Numbers

  1. D12.644w.360.024w.098w.525
  2. D12.776w.157w.057w.005w.525
  3. D12.776w.476.024w.104w.525
  4. D12.776w.543w.090w.525

AMA Style

References

  1. National Library of Medicine. beta-Arrestins. Medical Subject Headings (MeSH). 2026. Unique ID D000071557. http://id.nlm.nih.gov/mesh/2026/D000071557
  2. beta-Arrestins. In: Wikidata. https://www.wikidata.org/wiki/Q76500524