Phenomena and Processes

beta-Lactam Resistance

Nonsusceptibility of bacteria to the action of the beta-lactam antibiotics. Mechanisms responsible for beta-lactam resistance may be degradation of antibiotics by BETA-LACTAMASES, failure of antibiotics to penetrate, or low-affinity binding of antibiotics to targets.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Nonsusceptibility of bacteria to the action of the beta-lactam antibiotics. Mechanisms responsible for beta-lactam resistance may be degradation of antibiotics by BETA-LACTAMASES, failure of antibiotics to penetrate, or low-affinity binding of antibiotics to targets.

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Synonyms

9 entry terms
  • beta-Lactam Resistant
  • beta-Lactamase Resistance
  • beta-Lactamase Resistant
  • Resistance, beta-Lactamase
  • Resistant, beta-Lactamase
  • beta Lactam Resistance
  • beta Lactam Resistant
  • beta Lactamase Resistance
  • beta Lactamase Resistant

MeSH Record

Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethnology, genetics, immunology, physiology, radiation effects.

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Indexing Annotation

general or unspecified; prefer specifics

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History Note

1995

MeSH Record

Previous Indexing

  • Drug Resistance, Microbial (1974-1994)
  • Lactams/pharmacology (1974-1994)

MeSH Hierarchy

Tree Numbers

  1. G06.099.225.500
  2. G06.225w.347.500
  3. G07.690.773.984w.269w.347.500

AMA Style

References

  1. National Library of Medicine. beta-Lactam Resistance. Medical Subject Headings (MeSH). 2026. Unique ID D018440. http://id.nlm.nih.gov/mesh/2026/D018440
  2. beta-Lactam Resistance. In: Wikidata. https://www.wikidata.org/wiki/Q71230772