Chemicals and Drugs

beta 2-Glycoprotein I

A 44-kDa highly glycosylated plasma protein that binds phospholipids including CARDIOLIPIN; APOLIPOPROTEIN E RECEPTOR; membrane phospholipids, and other anionic phospholipid-containing moieties. It plays a role in coagulation and apoptotic processes. Formerly known as apolipoprotein H, it is an autoantigen in patients with ANTIPHOSPHOLIPID ANTIBODIES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A 44-kDa highly glycosylated plasma protein that binds phospholipids including CARDIOLIPIN; APOLIPOPROTEIN E RECEPTOR; membrane phospholipids, and other anionic phospholipid-containing moieties. It plays a role in coagulation and apoptotic processes. Formerly known as apolipoprotein H, it is an autoantigen in patients with ANTIPHOSPHOLIPID ANTIBODIES.

MeSH Record

Classification

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

12 entry terms
  • Anticardiolipin Cofactor
  • Apo H
  • Apolipoprotein H
  • EC-VMFa
  • Endothelial Cell-Viability Maintaining Factor
  • beta(2)GPI
  • beta2-Glycoprotein I
  • Cofactor, Anticardiolipin
  • EC VMFa
  • Endothelial Cell Viability Maintaining Factor
  • beta 2 Glycoprotein I
  • beta2 Glycoprotein I

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2007; BETA 2-GLYCOPROTEIN I (NM) 1979-2006

MeSH Record

Previous Indexing

  • Glycoproteins (1967-2006)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. beta 2-Glycoprotein I. Medical Subject Headings (MeSH). 2026. Unique ID D053482. http://id.nlm.nih.gov/mesh/2026/D053482
  2. beta 2-Glycoprotein I. In: Wikidata. https://www.wikidata.org/wiki/Q648315