Chemicals and Drugs

beta Subunit Luteinizing Hormone

The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

10 entry terms
  • ICSH, beta Subunit
  • LH, beta Subunit
  • LH-beta
  • Luteinizing Hormone, beta Chain
  • Luteinizing Hormone, beta Polypeptide Chain
  • Luteinizing Hormone, beta Subunit
  • Lutropin, beta Subunit
  • Lutropin-beta
  • LH beta
  • Lutropin beta

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2003; use LUTEINIZING HORMONE, BETA SUBUNIT (NM) 1983-2002

MeSH Record

Previous Indexing

  • Luteinizing Hormone (1974-2002)

MeSH Hierarchy

Tree Numbers

  1. D06.472w.699w.322w.576.463w.500
  2. D06.472w.699w.631.525.343.463w.500
  3. D12.644w.548w.691.525.343.463w.500

AMA Style

References

  1. National Library of Medicine. beta Subunit Luteinizing Hormone. Medical Subject Headings (MeSH). 2026. Unique ID D037101. http://id.nlm.nih.gov/mesh/2026/D037101
  2. beta Subunit Luteinizing Hormone. In: Wikidata. https://www.wikidata.org/wiki/Q21121608