Chemicals and Drugs

mRNA Vaccines

Vaccines formulated with recombinant mRNAs which are taken up by the host cells that translate the mRNA and present the translated proteins to the immune system as antigens in a manner similar to that which would occur during natural infection. This induces humoral and cellular immune responses against the encoded antigen.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Vaccines formulated with recombinant mRNAs which are taken up by the host cells that translate the mRNA and present the translated proteins to the immune system as antigens in a manner similar to that which would occur during natural infection. This induces humoral and cellular immune responses against the encoded antigen.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

17 entry terms
  • Messenger RNA Vaccines
  • mRNA Vaccine
  • Vaccine, mRNA
  • Naked RNA Vaccines
  • RNA Vaccine
  • RNA Vaccines
  • Self-Amplifying RNA Vaccine
  • Trans Amplifying RNA Vaccine
  • saRNA Vaccine
  • taRNA Vaccine
  • RNA Vaccine, Self-Amplifying
  • Self Amplifying RNA Vaccine
  • Vaccine, RNA
  • Vaccine, Self-Amplifying RNA
  • Vaccine, saRNA
  • Vaccine, taRNA
  • Vaccines, RNA

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2022

MeSH Record

Previous Indexing

  • Vaccines, DNA (2001-2021)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. mRNA Vaccines. Medical Subject Headings (MeSH). 2026. Unique ID D000087503. http://id.nlm.nih.gov/mesh/2026/D000087503
  2. mRNA Vaccines. In: Wikipedia. https://en.wikipedia.org/wiki/MRNA_vaccine
  3. mRNA Vaccines. In: Wikidata. https://www.wikidata.org/wiki/Q85795487