Phenomena and Processes

myc Genes

Family of retrovirus-associated DNA sequences (myc) originally isolated from an avian myelocytomatosis virus. The proto-oncogene myc (c-myc) codes for a nuclear protein which is involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Truncation of the first exon, which appears to regulate c-myc expression, is crucial for tumorigenicity. The human c-myc gene is located at 8q24 on the long arm of chromosome 8.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Family of retrovirus-associated DNA sequences (myc) originally isolated from an avian myelocytomatosis virus. The proto-oncogene myc (c-myc) codes for a nuclear protein which is involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Truncation of the first exon, which appears to regulate c-myc expression, is crucial for tumorigenicity. The human c-myc gene is located at 8q24 on the long arm of chromosome 8.

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Synonyms

47 entry terms
  • Genes, myc
  • Gene, myc
  • myc Gene
  • L-myc Genes
  • L-myc Proto-Oncogenes
  • N-myc Genes
  • N-myc Proto-Oncogenes
  • c-myc Genes
  • c-myc Proto-Oncogenes
  • myc Oncogene
  • v-myc Genes
  • v-myc Oncogenes
  • Gene, L-myc
  • Gene, N-myc
  • Gene, c-myc
  • Gene, v-myc
  • Genes, L-myc
  • Genes, N-myc
  • Genes, c-myc
  • Genes, v-myc
  • L myc Genes
  • L myc Proto Oncogenes
  • L-myc Gene
  • L-myc Proto-Oncogene
  • N myc Genes
  • N myc Proto Oncogenes
  • N-myc Gene
  • N-myc Proto-Oncogene
  • Oncogene, myc
  • Oncogene, v-myc
  • Oncogenes, myc
  • Oncogenes, v-myc
  • Proto-Oncogene, L-myc
  • Proto-Oncogene, N-myc
  • Proto-Oncogene, c-myc
  • Proto-Oncogenes, L-myc
  • Proto-Oncogenes, N-myc
  • Proto-Oncogenes, c-myc
  • c myc Genes
  • c myc Proto Oncogenes
  • c-myc Gene
  • c-myc Proto-Oncogene
  • myc Oncogenes
  • v myc Genes
  • v myc Oncogenes
  • v-myc Gene
  • v-myc Oncogene

MeSH Record

Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.

MeSH Record

Indexing Annotation

myc stands for "MYeloCytomatosis"

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History Note

91; was MYC GENES see ONCOGENES 1985-90

MeSH Record

Previous Indexing

  • Genes, Viral (1982)
  • Oncogenes (1983-1990)

MeSH Hierarchy

Tree Number

  1. G05.360w.340w.024.340w.375.500w.791.420w

AMA Style

References

  1. National Library of Medicine. myc Genes. Medical Subject Headings (MeSH). 2026. Unique ID D016259. http://id.nlm.nih.gov/mesh/2026/D016259
  2. myc Genes. In: Wikipedia. https://en.wikipedia.org/wiki/MYC
  3. myc Genes. In: Wikidata. https://www.wikidata.org/wiki/Q20969939