Chemicals and Drugs

p-Chloroamphetamine

Chlorinated analog of AMPHETAMINE. Potent neurotoxin that causes release and eventually depletion of serotonin in the CNS. It is used as a research tool.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Chlorinated analog of AMPHETAMINE. Potent neurotoxin that causes release and eventually depletion of serotonin in the CNS. It is used as a research tool.

Chemical Identity

Chemical Information

Molecular Formula
C9H12ClN
Molecular Weight
169.65 g/mol
CAS Registry No.
64-12-0
IUPAC Name
1-(4-chlorophenyl)propan-2-amine
InChIKey
WWPITPSIWMXDPE-UHFFFAOYSA-N
SMILES
CC(CC1=CC=C(C=C1)Cl)N
MeSH Unique ID
D010133
Source
PubChem CID 3127

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

12 entry terms
  • Parachloroamphetamine
  • p-Chloramphetamine
  • para-Chloroamphetamine
  • p Chloramphetamine
  • p Chloroamphetamine
  • para Chloroamphetamine
  • LY-121860
  • Ly-123362
  • LY 121860
  • LY121860
  • Ly 123362
  • Ly123362

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under AMPHETAMINES 1975-90

MeSH Record

Previous Indexing

  • Amphetamine (1966-1974)
  • Chlorine (1966-1974)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. p-Chloroamphetamine. Medical Subject Headings (MeSH). 2026. Unique ID D010133. http://id.nlm.nih.gov/mesh/2026/D010133
  2. p-Chloroamphetamine. In: Wikipedia. https://en.wikipedia.org/wiki/Para-Chloroamphetamine
  3. p-Chloroamphetamine. In: Wikidata. https://www.wikidata.org/wiki/Q229944
  4. p-Chloroamphetamine. In: PubChem Compound. CID 3127. https://pubchem.ncbi.nlm.nih.gov/compound/3127