Phenomena and Processes

pX Genes

DNA sequences that form the coding region for at least three proteins which regulate the expression of HUMAN T-LYMPHOTROPIC VIRUS 1 and HUMAN T-LYMPHOTROPIC VIRUS 2. The proteins are p21(x), p27(rex), and p40(tax). The tax (trans-activator x) and rex (regulator x) genes are part of pX but are in overlapping reading frames. X was the original designation for the sequences or region (at that time of unknown function) in the long open reading frame (lor) which is now called pX.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

DNA sequences that form the coding region for at least three proteins which regulate the expression of HUMAN T-LYMPHOTROPIC VIRUS 1 and HUMAN T-LYMPHOTROPIC VIRUS 2. The proteins are p21(x), p27(rex), and p40(tax). The tax (trans-activator x) and rex (regulator x) genes are part of pX but are in overlapping reading frames. X was the original designation for the sequences or region (at that time of unknown function) in the long open reading frame (lor) which is now called pX.

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Synonyms

43 entry terms
  • Genes, lor
  • Genes, pX
  • Gene, lor
  • Gene, pX
  • lor Gene
  • lor Genes
  • pX Gene
  • Genes, rex
  • Genes, tax
  • HTLV-I rex Genes
  • HTLV-I tax Genes
  • HTLV-II rex Genes
  • HTLV-II tax Genes
  • rex Genes
  • tax Genes
  • Gene, HTLV-I rex
  • Gene, HTLV-I tax
  • Gene, HTLV-II rex
  • Gene, HTLV-II tax
  • Gene, rex
  • Gene, tax
  • Genes, HTLV-I rex
  • Genes, HTLV-I tax
  • Genes, HTLV-II rex
  • Genes, HTLV-II tax
  • HTLV I rex Genes
  • HTLV I tax Genes
  • HTLV II rex Genes
  • HTLV II tax Genes
  • HTLV-I rex Gene
  • HTLV-I tax Gene
  • HTLV-II rex Gene
  • HTLV-II tax Gene
  • rex Gene
  • rex Gene, HTLV-I
  • rex Gene, HTLV-II
  • rex Genes, HTLV-I
  • rex Genes, HTLV-II
  • tax Gene
  • tax Gene, HTLV-I
  • tax Gene, HTLV-II
  • tax Genes, HTLV-I
  • tax Genes, HTLV-II

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Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.

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History Note

91; LOR PROTEINS & PX PROTEINS were see TRANS-ACTIVATORS 1990

MeSH Record

Previous Indexing

  • Genes, Regulator (1984-1990)
  • Genes, Viral (1984-1990)

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References

  1. National Library of Medicine. pX Genes. Medical Subject Headings (MeSH). 2026. Unique ID D016355. http://id.nlm.nih.gov/mesh/2026/D016355
  2. pX Genes. In: Wikidata. https://www.wikidata.org/wiki/Q71227114