Chemicals and Drugs

rev Gene Products

Trans-acting nuclear proteins whose functional expression are required for retroviral replication. Specifically, the rev gene products are required for processing and translation of the gag and env mRNAs, and thus rev regulates the expression of the viral structural proteins. rev can also regulate viral regulatory proteins. A cis-acting antirepression sequence (CAR) in env, also known as the rev-responsive element (RRE), is responsive to the rev gene product. Rev is short for regulator of virion.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Trans-acting nuclear proteins whose functional expression are required for retroviral replication. Specifically, the rev gene products are required for processing and translation of the gag and env mRNAs, and thus rev regulates the expression of the viral structural proteins. rev can also regulate viral regulatory proteins. A cis-acting antirepression sequence (CAR) in env, also known as the rev-responsive element (RRE), is responsive to the rev gene product. Rev is short for regulator of virion.

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Synonyms

4 entry terms
  • Gene Product, rev
  • Gene Products, rev
  • rev Protein
  • rev Gene Product

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Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

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History Note

91(90); was see under TRANS-ACTIVATORS 1990

MeSH Record

Previous Indexing

  • Retroviridae Proteins (1986-1989)
  • Viral Proteins (1986-1989)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.725w.076
  2. D12.776w.664w.962w.186
  3. D12.776w.964w.925w.984.385

AMA Style

References

  1. National Library of Medicine. rev Gene Products. Medical Subject Headings (MeSH). 2026. Unique ID D015694. http://id.nlm.nih.gov/mesh/2026/D015694
  2. rev Gene Products. In: Wikidata. https://www.wikidata.org/wiki/Q77947557