Structured Summary
Abstract
A dioxygenase and alkylation repair homolog that catalyzes the methylation of 5-carboxymethyl URIDINE to 5-methylcarboxymethyl uridine at the wobble position of the ANTICODON loop in TRANSFER RNA (tRNA) via its methyltransferase domain. It has a preference for tRNA (ARGININE) and tRNA (GLUTAMATE), and does not bind tRNA (LYSINE).
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Synonyms
7 entry terms
- AlkB Homolog 8, tRNA Methyltransferase
- Alkylated DNA Repair Protein Alkb Homolog 8
- Probable Alpha-Ketoglutarate-Dependent Dioxygenase ABH8
- S-Adenosyl-L-Methionine-Dependent tRNA Methyltransferase ABH8
- tRNA (Carboxymethyluridine(34)-5-O)-Methyltransferase ABH8
- Probable Alpha Ketoglutarate Dependent Dioxygenase ABH8
- S Adenosyl L Methionine Dependent tRNA Methyltransferase ABH8
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Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017
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AMA Style
References
- National Library of Medicine. tRNA Methyltransferase AlkB Homolog 8. Medical Subject Headings (MeSH). 2026. Unique ID D000071503. http://id.nlm.nih.gov/mesh/2026/D000071503
- tRNA Methyltransferase AlkB Homolog 8. In: Wikidata. https://www.wikidata.org/wiki/Q21131652