Chemicals and Drugs

7-Alkoxycoumarin O-Dealkylase

A drug-metabolizing enzyme found in the hepatic, placental and intestinal microsomes that metabolizes 7-alkoxycoumarin to 7-hydroxycoumarin. The enzyme is cytochrome P-450- dependent.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A drug-metabolizing enzyme found in the hepatic, placental and intestinal microsomes that metabolizes 7-alkoxycoumarin to 7-hydroxycoumarin. The enzyme is cytochrome P-450- dependent.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

27 entry terms
  • 7-Ethoxycoumarin Dealkylase
  • 7-Ethoxycoumarin Hydroxylase
  • 7-Ethoxycoumarin Monooxygenase
  • 7-Ethoxycoumarin O-De-Ethylase
  • 7-Ethoxycoumarin O-Dealkylase
  • 7-Ethoxycoumarin O-Deethylase
  • 7-Propoxycoumarin O-Depropylase
  • Cytochrome P-450-Dependent O-Dealkylase
  • Ethoxycoumarin Deethylase
  • Ethoxycoumarin O-Deethylase
  • 7 Alkoxycoumarin O Dealkylase
  • 7 Ethoxycoumarin Dealkylase
  • 7 Ethoxycoumarin Hydroxylase
  • 7 Ethoxycoumarin Monooxygenase
  • 7 Ethoxycoumarin O De Ethylase
  • 7 Ethoxycoumarin O Dealkylase
  • 7 Ethoxycoumarin O Deethylase
  • 7 Propoxycoumarin O Depropylase
  • Cytochrome P 450 Dependent O Dealkylase
  • Dealkylase, 7-Ethoxycoumarin
  • Deethylase, Ethoxycoumarin
  • Ethoxycoumarin O Deethylase
  • Hydroxylase, 7-Ethoxycoumarin
  • Monooxygenase, 7-Ethoxycoumarin
  • O-Deethylase, 7-Ethoxycoumarin
  • O-Depropylase, 7-Propoxycoumarin
  • P-450-Dependent O-Dealkylase, Cytochrome

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

90

MeSH Record

Previous Indexing

  • Oxygenases (1966-1989)

MeSH Hierarchy

Tree Number

  1. D08.811w.682w.690w.708.170w.010.024

AMA Style

References

  1. National Library of Medicine. 7-Alkoxycoumarin O-Dealkylase. Medical Subject Headings (MeSH). 2026. Unique ID D015660. http://id.nlm.nih.gov/mesh/2026/D015660
  2. 7-Alkoxycoumarin O-Dealkylase. In: Wikidata. https://www.wikidata.org/wiki/Q78027560