Chemicals and Drugs

ADAM Proteins

A family of membrane-anchored glycoproteins that contain a disintegrin and metalloprotease domain. They are responsible for the proteolytic cleavage of many transmembrane proteins and the release of their extracellular domain.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of membrane-anchored glycoproteins that contain a disintegrin and metalloprotease domain. They are responsible for the proteolytic cleavage of many transmembrane proteins and the release of their extracellular domain.

MeSH Record

Classification

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MeSH Record

Synonyms

3 entry terms
  • A Disintegrin and Metalloprotease Protein
  • A Disintegrin and Metalloprotease Proteins
  • ADAM (A Disintegrin and Metalloprotease) Proteins

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006

MeSH Hierarchy

Tree Numbers

  1. D08.811w.277w.656w.675w.374w.102w
  2. D09w.400w.430w.500w
  3. D12.776w.395w.033w

AMA Style

References

  1. National Library of Medicine. ADAM Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D051722. http://id.nlm.nih.gov/mesh/2026/D051722
  2. ADAM Proteins. In: Wikipedia. https://en.wikipedia.org/wiki/ADAM_(protein)
  3. ADAM Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q290049