Diseases

Acquired Immunodeficiency Syndrome

An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.

MeSH Record

Classification

Broader headings

Related Concepts

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See Also

MeSH Record

Synonyms

15 entry terms
  • AIDS
  • Acquired Immune Deficiency Syndrome
  • Acquired Immuno-Deficiency Syndrome
  • Immunodeficiency Syndrome, Acquired
  • Immunologic Deficiency Syndrome, Acquired
  • Acquired Immuno Deficiency Syndrome
  • Acquired Immuno-Deficiency Syndromes
  • Acquired Immunodeficiency Syndromes
  • Immuno-Deficiency Syndrome, Acquired
  • Immuno-Deficiency Syndromes, Acquired
  • Immunodeficiency Syndromes, Acquired
  • Syndrome, Acquired Immuno-Deficiency
  • Syndrome, Acquired Immunodeficiency
  • Syndromes, Acquired Immuno-Deficiency
  • Syndromes, Acquired Immunodeficiency

MeSH Record

Aspects Covered

36 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, transmission, urine, veterinary, virology.

MeSH Record

Indexing Annotation

caused by HIV; coord IM with HIV-1 or HIV-2 (IM) if pertinent; /epidemiol: consider also HIV SEROPREVALENCE; AIDS-RELATED OPPORTUNISTIC INFECTIONS is available if particularly discussed: see note there; for lymphoma with AIDS, use LYMPHOMA, AIDS-RELATED

MeSH Record

History Note

83

MeSH Record

Previous Indexing

  • Immunologic Deficiency Syndromes (1979-1982)

MeSH Hierarchy

Tree Numbers

  1. C01w.221w.250w.875w.040w
  2. C01w.221w.812w.640.400w.040w
  3. C01w.778w.640.400w.040w
  4. C01w.925w.782.815.616.400w.040w
  5. C01w.925w.813.400w.040w
  6. C01w.925w.839w.040w
  7. C12.100w.937w.640.400w.040w
  8. C20w.673w.480w.040w

AMA Style

References

  1. National Library of Medicine. Acquired Immunodeficiency Syndrome. Medical Subject Headings (MeSH). 2026. Unique ID D000163. http://id.nlm.nih.gov/mesh/2026/D000163
  2. Acquired Immunodeficiency Syndrome. In: Wikipedia. https://en.wikipedia.org/wiki/HIV/AIDS
  3. Acquired Immunodeficiency Syndrome. In: Wikidata. https://www.wikidata.org/wiki/Q12199