Ado-Trastuzumab Emtansine

Structured Summary

Abstract

Immunotoxin that consists of humanized monoclonal anti-HER2 antibody TRASTUZUMAB covalently linked to anti-microtubule agent MAYTANSINOID DM1 for treatment of metastatic breast cancer in patients who previously received trastuzumab and a TAXANES, separately or in combination.

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms

Trastuzumab Emtansine
Ado Trastuzumab Emtansine
Kadcyla
Trastuzumab-DM1
Trastuzumab-DM1 Conjugate
huN901-DM1
Trastuzumab DM1
Trastuzumab DM1 Conjugate
huN901 DM1
huN901DM1

MeSH Record

Aspects Covered

22 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2020 (2010)

MeSH Hierarchy

Tree Numbers

D02 w.540 w.505 w.495 w.500w
D04 w.345 w.295.500 w.500w
D12.776 w.124 w.486.485.114 w.224 w.060 w.875 w.500w
D12.776 w.124 w.790.651.114 w.224 w.060 w.875 w.500w
D12.776 w.377 w.715.548.114 w.224 w.200 w.875 w.500w

AMA Style

References

National Library of Medicine. Ado-Trastuzumab Emtansine. Medical Subject Headings (MeSH). 2026. Unique ID D000080044. http://id.nlm.nih.gov/mesh/2026/D000080044
Ado-Trastuzumab Emtansine. In: Wikipedia. https://en.wikipedia.org/wiki/Trastuzumab_emtansine
Ado-Trastuzumab Emtansine. In: Wikidata. https://www.wikidata.org/wiki/Q3997863