Chemicals and Drugs

Macrolides

A group of often glycosylated macrocyclic compounds formed by chain extension of multiple PROPIONATES cyclized into a large (typically 12, 14, or 16)-membered lactone. Macrolides belong to the POLYKETIDES class of natural products, and many members exhibit ANTIBIOTIC properties.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A group of often glycosylated macrocyclic compounds formed by chain extension of multiple PROPIONATES cyclized into a large (typically 12, 14, or 16)-membered lactone. Macrolides belong to the POLYKETIDES class of natural products, and many members exhibit ANTIBIOTIC properties.

MeSH Record

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MeSH Record

Synonyms

1 entry terms
  • Macrolide

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

96

MeSH Hierarchy

Tree Numbers

  1. D02w.540w.505w
  2. D02w.540w.576w.500w
  3. D04w.345w.674w.500w

MeSH Record

NLM Classification

QV 350

AMA Style

References

  1. National Library of Medicine. Macrolides. Medical Subject Headings (MeSH). 2026. Unique ID D018942. http://id.nlm.nih.gov/mesh/2026/D018942
  2. Macrolides. In: Wikipedia. https://en.wikipedia.org/wiki/Macrolide
  3. Macrolides. In: Wikidata. https://www.wikidata.org/wiki/Q422687