Chemicals and Drugs

Tylosin

Macrolide antibiotic obtained from cultures of Streptomyces fradiae. The drug is effective against many microorganisms in animals but not in humans.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Macrolide antibiotic obtained from cultures of Streptomyces fradiae. The drug is effective against many microorganisms in animals but not in humans.

Chemical Identity

Chemical Information

Molecular Formula
C46H77NO17
Molecular Weight
916.1 g/mol
CAS Registry No.
1401-69-0
IUPAC Name
2-[(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-15-[[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde
InChIKey
WBPYTXDJUQJLPQ-VMXQISHHSA-N
SMILES
CC[C@@H]1[C@H](/C=C(/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)C)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)O)N(C)C)O)CC=O)C)\C)CO[C@H]4[C@@H]([C@@H]([C@@H]([C@H](O4)C)O)OC)OC
MeSH Unique ID
D015645
Source
PubChem CID 5280440

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • Fradizine
  • Tylosine
  • Tylan
  • Tylosin Hydrochloride
  • Tylosin Tartrate
  • Tylosin Tartrate (Salt)
  • Hydrochloride, Tylosin
  • Tartrate, Tylosin

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

do not use /biosyn unless by living matter

MeSH Record

History Note

90; was see LEUCOMYCINS 1981-89; was see under ANTIBIOTICS 1964-80

MeSH Record

Previous Indexing

  • Antibiotics (1966-1980)
  • Leucomycins (1981-1989)

MeSH Hierarchy

Tree Number

  1. D02w.540w.505w.905w

AMA Style

References

  1. National Library of Medicine. Tylosin. Medical Subject Headings (MeSH). 2026. Unique ID D015645. http://id.nlm.nih.gov/mesh/2026/D015645
  2. Tylosin. In: Wikipedia. https://en.wikipedia.org/wiki/Tylosin
  3. Tylosin. In: Wikidata. https://www.wikidata.org/wiki/Q411462
  4. Tylosin. In: PubChem Compound. CID 5280440. https://pubchem.ncbi.nlm.nih.gov/compound/5280440