Chemicals and Drugs

Antimycin A

An antibiotic substance produced by Streptomyces species. It inhibits mitochondrial respiration and may deplete cellular levels of ATP. Antimycin A1 has been used as a fungicide, insecticide, and miticide. (From Merck Index, 12th ed)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An antibiotic substance produced by Streptomyces species. It inhibits mitochondrial respiration and may deplete cellular levels of ATP. Antimycin A1 has been used as a fungicide, insecticide, and miticide. (From Merck Index, 12th ed)

Chemical Identity

Chemical Information

Molecular Formula
C28H40N2O9
Molecular Weight
548.6 g/mol
CAS Registry No.
1397-94-0
IUPAC Name
[(2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] 3-methylbutanoate
InChIKey
UIFFUZWRFRDZJC-SBOOETFBSA-N
SMILES
CCCCCC[C@@H]1[C@H]([C@@H](OC(=O)[C@H]([C@H](OC1=O)C)NC(=O)C2=C(C(=CC=C2)NC=O)O)C)OC(=O)CC(C)C
MeSH Unique ID
D000968
Source
PubChem CID 14957

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

2 entry terms
  • Butanoic acid, 2(or 3)-methyl-, 3-((3-(formylamino)-2-hydroxybenzoyl)amino)-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl ester
  • Antimycin A1

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

66(64)

MeSH Hierarchy

Tree Number

  1. D02w.540w.576w.500w.750w

AMA Style

References

  1. National Library of Medicine. Antimycin A. Medical Subject Headings (MeSH). 2026. Unique ID D000968. http://id.nlm.nih.gov/mesh/2026/D000968
  2. Antimycin A. In: Wikipedia. https://en.wikipedia.org/wiki/Antimycin_A
  3. Antimycin A. In: Wikidata. https://www.wikidata.org/wiki/Q104708365
  4. Antimycin A. In: PubChem Compound. CID 14957. https://pubchem.ncbi.nlm.nih.gov/compound/14957