Chemicals and Drugs

Adrenergic Receptors

Cell-surface proteins that bind epinephrine and/or norepinephrine with high affinity and trigger intracellular changes. The two major classes of adrenergic receptors, alpha and beta, were originally discriminated based on their cellular actions but now are distinguished by their relative affinity for characteristic synthetic ligands. Adrenergic receptors may also be classified according to the subtypes of G-proteins with which they bind; this scheme does not respect the alpha-beta distinction.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Cell-surface proteins that bind epinephrine and/or norepinephrine with high affinity and trigger intracellular changes. The two major classes of adrenergic receptors, alpha and beta, were originally discriminated based on their cellular actions but now are distinguished by their relative affinity for characteristic synthetic ligands. Adrenergic receptors may also be classified according to the subtypes of G-proteins with which they bind; this scheme does not respect the alpha-beta distinction.

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

See Also

MeSH Record

Synonyms

11 entry terms
  • Adrenergic Receptor
  • Adrenoceptor
  • Adrenoceptors
  • Epinephrine Receptors
  • Receptors, Adrenergic
  • Receptors, Epinephrine
  • Receptor, Adrenergic
  • Norepinephrine Receptor
  • Norepinephrine Receptors
  • Receptors, Norepinephrine
  • Receptor, Norepinephrine

MeSH Record

Aspects Covered

17 allowable subheadings

Indexed with the subheadings administration & dosage, analysis, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

Indexing Annotation

general or unspecified; prefer specifics; coordinate with specific adrenergic agent

MeSH Record

History Note

73(71); RECEPTORS, NOREPINEPHRINE was heading 1993; NORADRENALINE RECEPTORS, NOREPINEPHRINE RECEPTORS, & RECEPTORS, NORADRENALINE were see RECEPTORS, NOREPINEPHRINE 1993

MeSH Record

Previous Indexing

  • Receptors, Drug (1968-1970)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.543w.750w.670w.300.300w
  2. D12.776w.543w.750w.695w.150.300w
  3. D12.776w.543w.750w.720w.330.300w

MeSH Record

NLM Classification

WL 102.8

AMA Style

References

  1. National Library of Medicine. Adrenergic Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D011941. http://id.nlm.nih.gov/mesh/2026/D011941
  2. Adrenergic Receptors. In: Wikipedia. https://en.wikipedia.org/wiki/Adrenergic_receptor
  3. Adrenergic Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q410568