Chemicals and Drugs

Cell Surface Receptors

Cell surface proteins that bind signalling molecules external to the cell with high affinity and convert this extracellular event into one or more intracellular signals that alter the behavior of the target cell (From Alberts, Molecular Biology of the Cell, 2nd ed, pp693-5). Cell surface receptors, unlike enzymes, do not chemically alter their ligands.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Cell surface proteins that bind signalling molecules external to the cell with high affinity and convert this extracellular event into one or more intracellular signals that alter the behavior of the target cell (From Alberts, Molecular Biology of the Cell, 2nd ed, pp693-5). Cell surface receptors, unlike enzymes, do not chemically alter their ligands.

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Classification

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Synonyms

8 entry terms
  • Cell Surface Receptor
  • Receptors, Cell Surface
  • Receptor, Cell Surface
  • Surface Receptor, Cell
  • Cell Surface Hormone Receptors
  • Endogenous Substances Receptors
  • Hormone Receptors, Cell Surface
  • Receptors, Endogenous Substances

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Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

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Indexing Annotation

general or unspecified; prefer specifics; coord IM with specific endogenous substance (IM); for hormone receptors in general coord HORMONES (IM) and RECEPTORS, CELL SURFACE (IM) or RECEPTORS, CYTOPLASMIC AND NUCLEAR (IM), for receptors of specific hormones, coord specific hormone or hormone group (IM) and precoord hormone receptor (e.g., RECEPTORS, ALDOSTERONE) (IM) or precoord hormone-group receptor (e.g., RECEPTORS, GLUCOCORTICOID) (IM)

MeSH Record

History Note

94; was RECEPTORS, ENDOGENOUS SUBSTANCES 1983-93; was RECEPTORS, HORMONE 1973-82; CELL RECEPTORS & RECEPTORS, BIOLOGIC were see RECEPTORS, ENDOGENOUS SUBSTANCES 1985-93; HORMONE RECEPTORS was see RECEPTORS, ENDOGENOUS SUBSTANCES 1975-93

MeSH Record

Previous Indexing

  • Receptors, Drug (1968-1972)

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AMA Style

References

  1. National Library of Medicine. Cell Surface Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D011956. http://id.nlm.nih.gov/mesh/2026/D011956
  2. Cell Surface Receptors. In: Wikipedia. https://en.wikipedia.org/wiki/Cell_surface_receptor
  3. Cell Surface Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q2476074