Chemicals and Drugs

Endoglin

A membrane glycoprotein and ANGIOGENESIS FACTOR that is expressed by cells of the VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; and MONOCYTES. It functions as a co-receptor for TRANSFORMING GROWTH FACTOR BETA and modulates CELL ADHESION. Mutations in the endoglin gene are associated with cases of HEREDITARY HEMORRHAGIC TELANGIECTASIA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A membrane glycoprotein and ANGIOGENESIS FACTOR that is expressed by cells of the VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; and MONOCYTES. It functions as a co-receptor for TRANSFORMING GROWTH FACTOR BETA and modulates CELL ADHESION. Mutations in the endoglin gene are associated with cases of HEREDITARY HEMORRHAGIC TELANGIECTASIA.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

3 entry terms
  • CD105 Antigen
  • Endoglin Protein
  • Antigen, CD105

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2017

MeSH Record

Previous Indexing

  • Antigens, CD (2006-2016)
  • Receptors, Cell Surface (2006-2016)

MeSH Hierarchy

Tree Number

  1. D12.776w.543w.750w.250

AMA Style

References

  1. National Library of Medicine. Endoglin. Medical Subject Headings (MeSH). 2026. Unique ID D000071063. http://id.nlm.nih.gov/mesh/2026/D000071063
  2. Endoglin. In: Wikidata. https://www.wikidata.org/wiki/Q3054016