Chemicals and Drugs

Adrenocorticotropic Hormone

An anterior pituitary hormone that stimulates the ADRENAL CORTEX and its production of CORTICOSTEROIDS. ACTH is a 39-amino acid polypeptide of which the N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Upon further tissue-specific processing, ACTH can yield ALPHA-MSH and corticotrophin-like intermediate lobe peptide (CLIP).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An anterior pituitary hormone that stimulates the ADRENAL CORTEX and its production of CORTICOSTEROIDS. ACTH is a 39-amino acid polypeptide of which the N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Upon further tissue-specific processing, ACTH can yield ALPHA-MSH and corticotrophin-like intermediate lobe peptide (CLIP).

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

See Also

MeSH Record

Synonyms

11 entry terms
  • 1-39 ACTH
  • ACTH
  • ACTH (1-39)
  • Adrenocorticotrophic Hormone
  • Adrenocorticotropin
  • Corticotrophin
  • Corticotrophin (1-39)
  • Corticotropin
  • Corticotropin (1-39)
  • Hormone, Adrenocorticotrophic
  • Hormone, Adrenocorticotropic

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2007, 1987-1993 (1963)

MeSH Hierarchy

Tree Numbers

  1. D06.472w.699w.327.935.531w.500w
  2. D06.472w.699w.631.525.600.531w.500w
  3. D12.644w.400w.400.935.531w.500w
  4. D12.644w.548w.365.935.531w.500w
  5. D12.644w.548w.691.525.690.531w.500w
  6. D12.776w.631w.650w.405.935.531w.500w

MeSH Record

NLM Classification

WK 515

AMA Style

References

  1. National Library of Medicine. Adrenocorticotropic Hormone. Medical Subject Headings (MeSH). 2026. Unique ID D000324. http://id.nlm.nih.gov/mesh/2026/D000324
  2. Adrenocorticotropic Hormone. In: Wikipedia. https://en.wikipedia.org/wiki/Adrenocorticotropic_hormone
  3. Adrenocorticotropic Hormone. In: Wikidata. https://www.wikidata.org/wiki/Q185690