Chemicals and Drugs

Corticotropin Receptors

Cell surface receptors that bind CORTICOTROPIN; (ACTH, adrenocorticotropic hormone) with high affinity and trigger intracellular changes. Pharmacology suggests there may be multiple ACTH receptors. An ACTH receptor has been cloned and belongs to a subfamily of G-protein-coupled receptors. In addition to the adrenal cortex, ACTH receptors are found in the brain and immune systems.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Cell surface receptors that bind CORTICOTROPIN; (ACTH, adrenocorticotropic hormone) with high affinity and trigger intracellular changes. Pharmacology suggests there may be multiple ACTH receptors. An ACTH receptor has been cloned and belongs to a subfamily of G-protein-coupled receptors. In addition to the adrenal cortex, ACTH receptors are found in the brain and immune systems.

MeSH Record

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Synonyms

13 entry terms
  • ACTH Receptor
  • ACTH Receptors
  • Adrenocorticotropic Hormone Receptor
  • Adrenocorticotropic Hormone Receptors
  • Corticotropin Receptor
  • Receptors, ACTH
  • Receptors, Adrenocorticotropic Hormone
  • Receptors, Corticotropin
  • Hormone Receptor, Adrenocorticotropic
  • Hormone Receptors, Adrenocorticotropic
  • Receptor, ACTH
  • Receptor, Adrenocorticotropic Hormone
  • Receptor, Corticotropin

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

94; was CORTICOTROPIN RECEPTOR (NM) 1981-93; CORTICOTROPIN RECEPTORS & ACTH RECEPTORS were SYs 1983-93

MeSH Record

Previous Indexing

  • Receptors, Cell Surface (1981-1986)
  • Receptors, Pituitary Hormone (1987-1993)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.543w.750w.720w.600w.285
  2. D12.776w.543w.750w.750w.555w.285
  3. D12.776w.543w.750w.750w.660.285

AMA Style

References

  1. National Library of Medicine. Corticotropin Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D018043. http://id.nlm.nih.gov/mesh/2026/D018043
  2. Corticotropin Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q58674681