Chemicals and Drugs

Advanced Glycation End Products

A heterogeneous group of compounds derived from rearrangements, oxidation, and cross-linking reactions that follow from non-enzymatic glycation of amino groups in PROTEINS; LIPIDS; or NUCLEIC ACIDS. Their accumulation in vivo accelerates under hyperglycemic, oxidative, or inflammatory conditions. Heat also accelerates the formation of advanced glycation end products (AGEs) such seen with the browning of food during cooking.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A heterogeneous group of compounds derived from rearrangements, oxidation, and cross-linking reactions that follow from non-enzymatic glycation of amino groups in PROTEINS; LIPIDS; or NUCLEIC ACIDS. Their accumulation in vivo accelerates under hyperglycemic, oxidative, or inflammatory conditions. Heat also accelerates the formation of advanced glycation end products (AGEs) such seen with the browning of food during cooking.

MeSH Record

Classification

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MeSH Record

Synonyms

21 entry terms
  • Advanced Glycation End Product
  • Advanced Glycation Endproduct
  • Advanced Glycation Endproducts
  • Glycation End Products, Advanced
  • Glycation Endproducts, Advanced
  • Glycotoxins
  • Glycation Endproduct, Advanced
  • Advanced Maillard Reaction End Product
  • Advanced Maillard Reaction End Products
  • Glycated Lipids
  • Maillard Product
  • Maillard Products
  • Maillard Reaction End Product
  • Maillard Reaction End Products
  • Maillard Reaction Product
  • Maillard Reaction Products
  • Lipids, Glycated
  • Product, Maillard Reaction
  • Products, Maillard
  • Products, Maillard Reaction
  • Reaction Products, Maillard

MeSH Record

Aspects Covered

27 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2018 (1993)

MeSH Record

Previous Indexing

  • Glycosylation (1988-1992)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.205w
  2. D23.946w.381w

AMA Style

References

  1. National Library of Medicine. Advanced Glycation End Products. Medical Subject Headings (MeSH). 2026. Unique ID D017127. http://id.nlm.nih.gov/mesh/2026/D017127
  2. Advanced Glycation End Products. In: Wikipedia. https://en.wikipedia.org/wiki/Advanced_glycation_end-product
  3. Advanced Glycation End Products. In: Wikidata. https://www.wikidata.org/wiki/Q2556837