Chemicals and Drugs

Alprostadil

A potent vasodilator agent that increases peripheral blood flow.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A potent vasodilator agent that increases peripheral blood flow.

Chemical Identity

Chemical Information

Molecular Formula
C20H34O5
Molecular Weight
354.5 g/mol
CAS Registry No.
745-65-3
IUPAC Name
7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid
InChIKey
GMVPRGQOIOIIMI-DWKJAMRDSA-N
SMILES
CCCCC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1CCCCCCC(=O)O)O)O
MeSH Unique ID
D000527
Source
PubChem CID 5280723

MeSH Record

Classification

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

16 entry terms
  • Lipo-PGE1
  • PGE1
  • PGE1alpha
  • Prostaglandin E1
  • Prostaglandin E1alpha
  • Lipo PGE1
  • Caverject
  • Edex
  • Minprog
  • Muse
  • Prostavasin
  • Prostin VR
  • Prostine VR
  • Sugiran
  • Vasaprostan
  • Viridal

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

86; see VASOPROSTAN (NM) 1995-97

MeSH Record

Previous Indexing

  • Prostaglandins (1966-1974)
  • Prostaglandins E (1975-1985)

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

QU 90

AMA Style

References

  1. National Library of Medicine. Alprostadil. Medical Subject Headings (MeSH). 2026. Unique ID D000527. http://id.nlm.nih.gov/mesh/2026/D000527
  2. Alprostadil. In: Wikipedia. https://en.wikipedia.org/wiki/Prostaglandin_E1
  3. Alprostadil. In: Wikidata. https://www.wikidata.org/wiki/Q579348
  4. Alprostadil. In: PubChem Compound. CID 5280723. https://pubchem.ncbi.nlm.nih.gov/compound/5280723