Chemicals and Drugs

Prostaglandins E

(11 alpha,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid (PGE(1)); (5Z,11 alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (PGE(2)); and (5Z,11 alpha,13E,15S,17Z)-11,15-dihydroxy-9-oxoprosta-5,13,17-trien-1-oic acid (PGE(3)). Three of the six naturally occurring prostaglandins. They are considered primary in that no one is derived from another in living organisms. Originally isolated from sheep seminal fluid and vesicles, they are found in many organs and tissues and play a major role in mediating various physiological activities.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

(11 alpha,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid (PGE(1)); (5Z,11 alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (PGE(2)); and (5Z,11 alpha,13E,15S,17Z)-11,15-dihydroxy-9-oxoprosta-5,13,17-trien-1-oic acid (PGE(3)). Three of the six naturally occurring prostaglandins. They are considered primary in that no one is derived from another in living organisms. Originally isolated from sheep seminal fluid and vesicles, they are found in many organs and tissues and play a major role in mediating various physiological activities.

MeSH Record

Classification

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MeSH Record

Synonyms

1 entry terms
  • PGE

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

/chem syn permitted: do not convert to PROSTAGLANDINS E, SYNTHETIC

MeSH Record

History Note

75

MeSH Record

Previous Indexing

  • Prostaglandins (1966-1974)

MeSH Hierarchy

Tree Numbers

  1. D10w.251w.355w.255w.550w.250w
  2. D23.469.050w.175w.725w.250w

MeSH Record

NLM Classification

QU 91

AMA Style

References

  1. National Library of Medicine. Prostaglandins E. Medical Subject Headings (MeSH). 2026. Unique ID D011458. http://id.nlm.nih.gov/mesh/2026/D011458
  2. Prostaglandins E. In: Wikipedia. https://en.wikipedia.org/wiki/Prostaglandin_E
  3. Prostaglandins E. In: Wikidata. https://www.wikidata.org/wiki/Q4860325