Structured Summary
Abstract
A serine protease that is the complex of COMPLEMENT C3B and COMPLEMENT FACTOR BB. It cleaves multiple COMPLEMENT C3 into COMPLEMENT C3A (anaphylatoxin) and COMPLEMENT C3B in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY.
MeSH Record
Classification
Broader headings
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
9 entry terms
- Alternative Pathway C3 Convertase
- C3 Convertase (C3bBb)
- C3 Convertase, Alternative Pathway
- Complement 3 Convertase, Alternative Pathway
- Complement 3b-Associated Factor B-fragment Bb
- Complement C3 Convertase, Alternative Pathway
- Complement 3b Associated Factor B fragment Bb
- CVFBb
- Complement C3 Convertase, CVFBb
MeSH Record
Aspects Covered
28 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006 (1989); for CVFBB use COMPLEMENT FACTOR B 1985-2005
MeSH Record
Previous Indexing
- Complement C3 (1976-2005)
- Esterases (1976-2005)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Alternative Pathway Complement C3 Convertase. Medical Subject Headings (MeSH). 2026. Unique ID D051561. http://id.nlm.nih.gov/mesh/2026/D051561
- Alternative Pathway Complement C3 Convertase. In: Wikidata. https://www.wikidata.org/wiki/Q67999894