Structured Summary
Abstract
A serine protease that cleaves multiple COMPLEMENT C5 into COMPLEMENT C5A (anaphylatoxin) and COMPLEMENT C5B in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY. It is the complex of ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb) with an additional COMPLEMENT C3B, or C3bBb3b.
MeSH Record
Classification
Broader headings
Related Concepts
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
4 entry terms
- Alternative Pathway C5 Convertase
- C5 Convertase (C3bBb3b)
- C5 Convertase, Alternative Pathway
- Complement C5 Convertase, Alternative Pathway
MeSH Record
Aspects Covered
28 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006
MeSH Record
Previous Indexing
- Complement Activating Enzymes (1978-2005)
- Complement C5 (1976-2005)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Alternative Pathway Complement C5 Convertase. Medical Subject Headings (MeSH). 2026. Unique ID D051566. http://id.nlm.nih.gov/mesh/2026/D051566
- Alternative Pathway Complement C5 Convertase. In: Wikidata. https://www.wikidata.org/wiki/Q67999172