Chemicals and Drugs

Amino Acid Chloromethyl Ketones

Inhibitors of SERINE ENDOPEPTIDASES and sulfhydryl group-containing enzymes. They act as alkylating agents and are known to interfere in the translation process.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Inhibitors of SERINE ENDOPEPTIDASES and sulfhydryl group-containing enzymes. They act as alkylating agents and are known to interfere in the translation process.

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

3 entry terms
  • Peptide Chloromethyl Ketones
  • Chloromethyl Ketones, Peptide
  • Ketones, Peptide Chloromethyl

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

77

MeSH Record

Previous Indexing

  • Peptides (1966-1976)
  • specific amino acid (1966-1976)

MeSH Hierarchy

Tree Number

  1. D12.125w.065

AMA Style

References

  1. National Library of Medicine. Amino Acid Chloromethyl Ketones. Medical Subject Headings (MeSH). 2026. Unique ID D000590. http://id.nlm.nih.gov/mesh/2026/D000590
  2. Amino Acid Chloromethyl Ketones. In: Wikidata. https://www.wikidata.org/wiki/Q66022683