Chemicals and Drugs

Tosyllysine Chloromethyl Ketone

An inhibitor of SERINE ENDOPEPTIDASES. Acts as an alkylating agent and is known to interfere with the translation process.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An inhibitor of SERINE ENDOPEPTIDASES. Acts as an alkylating agent and is known to interfere with the translation process.

MeSH Record

Classification

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • Chlorotosylamidoaminoheptanone
  • TLCK
  • Tosyllysyl Chloromethane
  • Chloromethane, Tosyllysyl
  • Chloromethyl Ketone, Tosyllysine
  • Ketone, Tosyllysine Chloromethyl

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under AMINO ACID CHLOROMETHYL KETONES 1977-90; was see under LYSINE 1975-76

MeSH Record

Previous Indexing

  • Chlorine (1974)
  • Lysine (1974)
  • Tosyl Compounds (1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Tosyllysine Chloromethyl Ketone. Medical Subject Headings (MeSH). 2026. Unique ID D014107. http://id.nlm.nih.gov/mesh/2026/D014107
  2. Tosyllysine Chloromethyl Ketone. In: Wikidata. https://www.wikidata.org/wiki/Q77033202