Chemicals and Drugs

Aminopterin

A folic acid derivative used as a rodenticide that has been shown to be teratogenic.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A folic acid derivative used as a rodenticide that has been shown to be teratogenic.

Chemical Identity

Chemical Information

Molecular Formula
C19H20N8O5
Molecular Weight
440.4 g/mol
CAS Registry No.
54-62-6
IUPAC Name
(2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
InChIKey
TVZGACDUOSZQKY-LBPRGKRZSA-N
SMILES
C1=CC(=CC=C1C(=O)N[C@@H](CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=NC(=N3)N)N
MeSH Unique ID
D000630
Source
PubChem CID 169371

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

4 entry terms
  • Aminopterin Sodium
  • Aminopterin, Disodium Salt
  • Disodium Salt Aminopterin
  • Sodium, Aminopterin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Aminopterin. Medical Subject Headings (MeSH). 2026. Unique ID D000630. http://id.nlm.nih.gov/mesh/2026/D000630
  2. Aminopterin. In: Wikipedia. https://en.wikipedia.org/wiki/Aminopterin
  3. Aminopterin. In: Wikidata. https://www.wikidata.org/wiki/Q415734
  4. Aminopterin. In: PubChem Compound. CID 169371. https://pubchem.ncbi.nlm.nih.gov/compound/169371