Analytical, Diagnostic and Therapeutic Techniques, and Equipment

Area Under Curve

A statistical means of summarizing information from a series of measurements on one individual. It is frequently used in clinical pharmacology where the AUC from serum levels can be interpreted as the total uptake of whatever has been administered. As a plot of the concentration of a drug against time, after a single dose of medicine, producing a standard shape curve, it is a means of comparing the bioavailability of the same drug made by different companies. (From Winslade, Dictionary of Clinical Research, 1992)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A statistical means of summarizing information from a series of measurements on one individual. It is frequently used in clinical pharmacology where the AUC from serum levels can be interpreted as the total uptake of whatever has been administered. As a plot of the concentration of a drug against time, after a single dose of medicine, producing a standard shape curve, it is a means of comparing the bioavailability of the same drug made by different companies. (From Winslade, Dictionary of Clinical Research, 1992)

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

6 entry terms
  • AUC
  • Area Under Curves
  • Curve, Area Under
  • Curves, Area Under
  • Under Curve, Area
  • Under Curves, Area

MeSH Record

History Note

97

MeSH Hierarchy

Tree Numbers

  1. E05.318w.740w.200w
  2. G03w.787w.101w
  3. G07.690.725w.064w
  4. N06.850w.520w.830w.200w

AMA Style

References

  1. National Library of Medicine. Area Under Curve. Medical Subject Headings (MeSH). 2026. Unique ID D019540. http://id.nlm.nih.gov/mesh/2026/D019540
  2. Area Under Curve. In: Wikipedia. https://en.wikipedia.org/wiki/Area_under_the_curve_(pharmacokinetics)
  3. Area Under Curve. In: Wikidata. https://www.wikidata.org/wiki/Q16833590