Phenomena and Processes

Pharmacokinetics

Dynamic and kinetic mechanisms of exogenous chemical DRUG LIBERATION; ABSORPTION; BIOLOGICAL TRANSPORT; TISSUE DISTRIBUTION; BIOTRANSFORMATION; elimination; and DRUG TOXICITY as a function of dosage, and rate of METABOLISM. LADMER, ADME and ADMET are abbreviations for liberation, absorption, distribution, metabolism, elimination, and toxicology.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Dynamic and kinetic mechanisms of exogenous chemical DRUG LIBERATION; ABSORPTION; BIOLOGICAL TRANSPORT; TISSUE DISTRIBUTION; BIOTRANSFORMATION; elimination; and DRUG TOXICITY as a function of dosage, and rate of METABOLISM. LADMER, ADME and ADMET are abbreviations for liberation, absorption, distribution, metabolism, elimination, and toxicology.

MeSH Record

Classification

Broader headings

Narrower headings

MeSH Qualifier

Used as a Subheading

Pharmacokinetics is also a MeSH subheading (qualifier Q000493), attached to other headings to focus them on this aspect:

Used for the mechanism, dynamics and kinetics of exogenous chemical and drug absorption, biotransformation, distribution, release, transport, uptake and elimination as a function of dosage, extent and rate of metabolic processes.

Qualifier ID
Q000493
Qualifier Tree
Y07.070, Y08.040.060

Indexing annotation

subhead only; with exogenous chemicals only; includes "dynamics","absorption", "distribution", "uptake"; on the extent & rate of metabolism; not for pharmacologic effects or pharmacologic action ( = /pharmacology); see MeSH scope note in Introduction; indexing policy: Manual 19.8.53; DF: /pharmacokin or /PK

Subheading synonyms

  • tissue distribution
  • toxicokinetics

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MeSH Record

Synonyms

9 entry terms
  • Drug Kinetics
  • Kinetics, Drug
  • ADME
  • ADME-Tox
  • ADMET
  • Absorption, Distribution, Metabolism, Elimination, and Toxicology
  • Absorption, Distribution, Metabolism, and Elimination
  • LADMER
  • Liberation, Absorption, Distribution, Metabolism, Elimination, and Response

MeSH Record

Indexing Annotation

general or unspecified; prefer /pharmacokin with drugs

MeSH Record

History Note

88

MeSH Record

Previous Indexing

  • Kinetics (1966-1987)
  • specific Category D heading/metabolism (1966-1987)

MeSH Hierarchy

Tree Numbers

  1. G03w.787w
  2. G07.690.725w

MeSH Record

NLM Classification

QV 38

AMA Style

References

  1. National Library of Medicine. Pharmacokinetics. Medical Subject Headings (MeSH). 2026. Unique ID D010599. http://id.nlm.nih.gov/mesh/2026/D010599
  2. Pharmacokinetics. In: Wikipedia. https://en.wikipedia.org/wiki/Pharmacokinetics
  3. Pharmacokinetics. In: Wikidata. https://www.wikidata.org/wiki/Q323936