Phenomena and Processes

Biotransformation

The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the production of an active metabolite of an inactive parent compound. The alterations may be divided into METABOLIC DETOXICATION, PHASE I and METABOLIC DETOXICATION, PHASE II.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the production of an active metabolite of an inactive parent compound. The alterations may be divided into METABOLIC DETOXICATION, PHASE I and METABOLIC DETOXICATION, PHASE II.

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MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

Indexing Annotation

restrict to chemical changes of exogenous substances; IM general only; coordinate NIM with specific drug /pharmacokin (IM) or /metab; do not confuse with BIODEGRADATION, ENVIRONMENTAL

MeSH Record

History Note

70(66)

MeSH Hierarchy

Tree Numbers

  1. G03w.171w
  2. G03w.787w.225w
  3. G07.690.725w.225w

AMA Style

References

  1. National Library of Medicine. Biotransformation. Medical Subject Headings (MeSH). 2026. Unique ID D001711. http://id.nlm.nih.gov/mesh/2026/D001711
  2. Biotransformation. In: Wikipedia. https://en.wikipedia.org/wiki/Biotransformation
  3. Biotransformation. In: Wikidata. https://www.wikidata.org/wiki/Q864895