Structured Summary
Abstract
A Poly(A) RNA-binding protein that negatively regulates EGFR ENDOCYTOSIS. An increased risk for developing AMYOTROPHIC LATERAL SCLEROSIS 13 is observed in patients who have more than 23 CAG repeats in the ATXN2 gene coding sequence. Larger CAG expansions in the ATXN2 gene occur in SPINOCEREBELLAR ATAXIA 2 patients.
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Synonyms
12 entry terms
- ATXN2 Protein
- Ataxin-2 Protein
- Atx-2 Protein
- SCA2 Protein
- Spinocerebellar Ataxia Type 2 Protein
- Ataxin 2
- Ataxin 2 Protein
- Atx 2 Protein
- Protein, ATXN2
- Protein, Ataxin-2
- Protein, Atx-2
- Protein, SCA2
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Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
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History Note
2016; use SCA2 PROTEIN (NM) 1996-2015
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Previous Indexing
- Nerve Tissue Proteins (2005-2015)
- Proteins (1996-2005)
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AMA Style
References
- National Library of Medicine. Ataxin-2. Medical Subject Headings (MeSH). 2026. Unique ID D000067698. http://id.nlm.nih.gov/mesh/2026/D000067698
- Ataxin-2. In: Wikipedia. https://en.wikipedia.org/wiki/Ataxin-2
- Ataxin-2. In: Wikidata. https://www.wikidata.org/wiki/Q21171902