Chemicals and Drugs

Basiliximab

A chimeric murine-human monoclonal antibody that functions as an INTERLEUKIN 2 RECEPTOR antagonist by binding to the alpha chain (CD25 ANTIGEN) of the interleukin-2 receptor on the surface of activated T-LYMPHOCYTES. It is used in the prevention of acute graft rejection episodes in patients undergoing renal transplantation.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A chimeric murine-human monoclonal antibody that functions as an INTERLEUKIN 2 RECEPTOR antagonist by binding to the alpha chain (CD25 ANTIGEN) of the interleukin-2 receptor on the surface of activated T-LYMPHOCYTES. It is used in the prevention of acute graft rejection episodes in patients undergoing renal transplantation.

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

3 entry terms
  • CHI 621
  • SDZ CHI 621
  • Simulect

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2019 (1998)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.124w.486.485.114w.224w.060w.344w
  2. D12.776w.124w.790.651.114w.224w.060w.407w
  3. D12.776w.377w.715.548.114w.224w.200w.407w

AMA Style

References

  1. National Library of Medicine. Basiliximab. Medical Subject Headings (MeSH). 2026. Unique ID D000077552. http://id.nlm.nih.gov/mesh/2026/D000077552
  2. Basiliximab. In: Wikipedia. https://en.wikipedia.org/wiki/Basiliximab
  3. Basiliximab. In: Wikidata. https://www.wikidata.org/wiki/Q418702