Chemicals and Drugs

Benzopyrene Hydroxylase

A drug-metabolizing, cytochrome P-448 (P-450) enzyme which catalyzes the hydroxylation of benzopyrene to 3-hydroxybenzopyrene in the presence of reduced flavoprotein and molecular oxygen. Also acts on certain anthracene derivatives. An aspect of EC 1.14.14.1.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A drug-metabolizing, cytochrome P-448 (P-450) enzyme which catalyzes the hydroxylation of benzopyrene to 3-hydroxybenzopyrene in the presence of reduced flavoprotein and molecular oxygen. Also acts on certain anthracene derivatives. An aspect of EC 1.14.14.1.

MeSH Record

Classification

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MeSH Record

Synonyms

5 entry terms
  • Benzo(a)pyrene Hydroxylase
  • Benzo(a)pyrene Monooxygenase
  • Benzopyrene-3-Monooxygenase
  • Benzopyrene 3 Monooxygenase
  • Hydroxylase, Benzopyrene

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

a cytochrome

MeSH Record

History Note

91(75); was see under ARYL HYDROCARBON HYDROXYLASES 1977-90; was see under HYDROXYLASES 1975-76

MeSH Record

Previous Indexing

  • Benzopyrenes (1968-1974)
  • Hydroxylases (1968-1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Benzopyrene Hydroxylase. Medical Subject Headings (MeSH). 2026. Unique ID D001579. http://id.nlm.nih.gov/mesh/2026/D001579
  2. Benzopyrene Hydroxylase. In: Wikidata. https://www.wikidata.org/wiki/Q76618304